Based on real patient data, NIGHT & DAY shows not statistically significant difference in overnight corneal swelling compared to wearing no lens at all. While other manufacturers have presented information on “available oxygen,” “natural levels of oxygen” or “oxygen flux,” the advantage of NIGHT & DAY’s Dk/t of 175 is supported by real data on corneal swelling. Use of NIGHT & DAY Overnight Shows No Statistical Differences in Central Corneal Swelling Compared to Wearing No Lens at All7 Upon Awakening 1 Hour After Eyes Open 2 Hours After Eyes Open Swelling % Greater corneal swelling than no lens wear* Swelling % Greater corneal swelling than no lens wear* Swelling % Greater corneal swelling than no lens wear* PureVision 5.31 YES 1.96 YES 0.88 YES NIGHT & DAY 3.32 NO 1.17 NO 0.45 NO Baseline with no lens 2.86 — 0.41 — 0.18 — *Statistically significantly higher central corneal swelling, compared to no lens, p ≤ 0.05. NIGHT & DAY showed statistically significantly less overnight corneal swelling directly upon awakening after overnight wear as compared to PureVision Eyes wearing PureVision lenses showed statistically significantly higher corneal swelling amounts upon awakening and at both 1 and 2 hours after awakening as compared to no lens wear
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